Pharmacogenomics: tailoring Drug Therapy to Individual Patients
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Abstract
Pharmacogenomics, the study of how individual genetic variations influence drug res-ponse, holds tremendous potential for personalized medicine. This comprehensive lite-rature review explores the current landscape of pharmacogenomics, focusing on its role in tailoring drug therapy to individual patients.
The introduction provides an overview of pharmacogenomics, its definition, and his- torical development. The subsequent sections delve into key subtopics, including the influence of pharmacogenomic variants on drug metabolism, the identification of gene-tic biomarkers for drug efficacy and safety, pharmacogenomic testing approaches, and
clinical applications in various healthcare settings.
Ethical, legal, and social implications (ELSI) surrounding pharmacogenomics are dis-cussed, along with future directions and challenges in this field. Through a meticulous analysis of existing research articles, clinical guidelines, and reviews, this literature review highlights the significance of pharmacogenomics in optimizing drug therapy, im-
roving patient outcomes, and fostering the era of precision medicine.
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