Une capsule à base d’un dispositif inje cteur de micro- aiguilles chargées de ma cromolécules pour l ’administration orale ? A capsule based on a micro-needle injector device loaded with macromolecules for oral administration?
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Abstract
Depuis la découverte initiale de l’insuline en 1922, les recherches se poursuivent dans le but de découvrir de nouvelles méthodes d’administration de cette protéine.Cet article porte sur la conception de dispositifs injecteurs de micro-aiguilles (luminal unfolding microneedle injector : LUMI) pour permettre l’administration orale de macromolécules, notamment l’insuline sous forme de capsule.
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